CSR Biotech

🧬 RENAPT + MI-SIM: Tagging native proteins with precision In a recent Nature Chemical Biology study, researchers used RENAPT — an RNA editing-based protein tagging method — to label endogenous proteins without genetic overexpression. Our MI-SIM imaging clearly showed RENAPT’s high specificity, co-localising tagged proteins with organelles like lysosomes and mitochondria. The approach works in live cells and supports super-resolution imaging. 🔗Read more https://lnkd.in/dY-4w38j #Imaging #Biotech #Microscopy 

🔬Research spotlight: seeing lysosomal acidity in sharp detail In new Cell research, scientists uncovered how the transporter SLC7A11 regulates lysosomal pH — offering new clues into mechanisms behind Parkinson’s disease. Standard microscopy wouldn’t cut it. To distinguish membrane from lumen, the team turned to our MI-SIM super-resolution platform. With MI-SIM, they clearly visualised SLC7A11 forming ring-like structures around the lysosomal lumen — a pattern that would blur into overlap on a confocal system. We’re proud to see MI-SIM support this level of insight, click the link to read the paper 👉 https://lnkd.in/dyGwMyfS #CellBiology #Neuroscience #SuperResolution #Microscopy #Lysosomes

Welcoming our new Project R&D Manager 🇨🇳🇩🇪 We’re excited to share a few highlights from Raj’s recent trip to China, where he hit the ground running—meeting the team and exploring the local area. As Raj puts it: “What an incredible start to my journey! The team's warmth and welcoming spirit have made me feel right at home since day one. Beyond diving into optical setups, I've loved exploring local Chinese cuisine on weekend outings with colleagues – my chopstick skills are now almost as sharp as our new tech!” From sharing hotpot with the team to shaping ideas for upcoming projects, it’s been a great visit — and we can’t wait for him to bring that same energy to our growing German team. 📸 Rajwinder S. #Microscopy #Imaging #Biotech

We’d like to extend our sincere thanks to Uri Manor, invited Plenary Speaker at #MMC2025, for visiting our booth and for the fantastic exchange. His plenary talk on the latest #AI tools for massively accelerated #segmentation of #multidimensional imaging datasets was truly inspiring. The work he shared pushes the boundaries of what’s possible in biological imaging and analysis. We’re grateful for the opportunity to connect in person at this outstanding meeting, organized by the Royal Microscopical Society！ Here’s to continuing the conversations and driving innovation together! #SmartMicroscopy #Imaging #AI #MMC2025 #LifeSciences #Collaboration

🚀 WE'RE LIVE AT MMC2025 in MANCHESTER! The premier Microscience Microscopy Congress 2025 organized by the Royal Microscopical Society is now underway (July 1-3), we are excited to be part of this global gathering of microscopy innovation! ✨ Find us at Stand #423 Meet our application scientist Christiaan Stuut and have a chat about our latest technology! #mmc2025UK #Microscopy

🔬 New insights into how ARL3 mutations affect cilia—powered by MI-SIM imaging. A recent study in The FASEB Journal used CSR Biotech’s MI-SIM technology to visualise cilia structure in fibroblasts from patients with ARL3 (T31A) and ARL3 (T31A/C118F) mutations. MI-SIM revealed that in the T31A/C118F variant, the transport protein IFT88 accumulated at the tip of the cilia—unlike in wild-type cells, where it remained at the base. These structural changes were linked to disrupted transport, longer cilia, and altered gene expression in key pathways. This work deepens understanding of how specific ARL3 variants shape disease mechanisms at the cellular level. 📖https://lnkd.in/edC3cu79 #Disease #Biotechnology #MISIM

We’re excited to be partnering with Quorum Technologies to bring our MI‑SIM technology to Canada! 🇨🇦 This collaboration means researchers across Canada can now access our machine-intelligent structured illumination microscopy — combining real-time speed, high resolution, and low photobleaching with Quorum’s trusted local support. If you're looking to enhance your live-cell imaging with fast, flexible super-resolution, MI‑SIM is now closer than ever. Find out more → https://lnkd.in/etZv6wfR #Microscopy #LiveCellImaging

We had a great time hosting our SIM practical sessions during the EMBO course last week 🎉 A big thank you to all our online and onsite participants, we had a full house for both days! We'd also like to give a special shout-out to the organisers, Ivan Novotny, Michaela Blazikova and Marko Lampe. If you couldn’t make it and would like to learn more about our technology, we’d love to chat! #Microscopy #Imaging #Biotechnology

📢 We’re hiring in Heidelberg! 🇩🇪 We are growing our European team and looking for a proactive Office Administrator / All Rounder to keep things running smoothly. From admin and logistics to event support and team coordination, this role is perfect for someone who thrives in a dynamic, international environment. Ready to help shape the future of life science imaging? Apply now → https://lnkd.in/dA_CT9NU #StartupJobs #LifeSciences #Microscopy  

We’re ready for the course visitors — sessions start today! 🧪✨ We are on-site at the EMBO Practical Course on Super-Resolution Microscopy in Prague. Today and tomorrow, we’ll be hosting hands-on sessions exploring how MI-SIM pushes live-cell super-resolution further. #Microscopy #Biotech